منابع مشابه
Basic Molecular and Cell Biology Molecular genetics of common diseases
Coronary heart disease, essential hypertension, diabetes mellitus, senile dementia, manic depressive psychosis, schizophrenia, and other common diseases of adults tend to cluster in families. The familial aggregation of these disorders is rarely caused by a single gene defect; rather, it results from the cumulative interaction of a number of genes with environmental factors. These disorders are...
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Pneumoviruses are responsible for significant respiratory disease in their hosts and represent a major problemfor human and animal health. Pneumoviruses are members of the family Paramyxoviridae, subfamilyPneumovirinae and the virus particles consist of a negative-sense, nonsegmented RNA genome within a helical nucleocapsid structure enveloped in a lipid membrane derived from the ho...
متن کاملMolecular genetics of renal diseases.
Recent progress in molecular genetics has strongly influenced nephrology. Gene mutations have been identified which cause various monogenic hereditary renal diseases including Alport syndrome, autosomal dominant polycystic kidney disease, and tubular transporter disorders. The data obtained will be useful not only to develop new methods of diagnosis and treatment of such particular diseases but...
متن کاملMolecular Genetics and Epidemiology of Vitiligo
Background: Vitiligo is an acquired, idiopathic, and common depigmentation disorder of the skin that affects people of all ages and both sexes equally in the worldwide. Although etiology of the disease is unknown, there are theories such as environment and genetic factors. Methods: In this article, we collected and summarized the appropriate manuscripts regarding the epidemiology and gene...
متن کاملFormal Genetics of Humans: Multifactorial Inheritance and Common Diseases
8.1.1 Variation in Phenotypic Traits ................................. 264 8.1.2 Familial Resemblance and Heritability ................... 264 8.1.3 The Special Case of Twins ...................................... 267 8.1.4 Embedding a Single Measured Gene Infl uencing a Continuous Trait ................................ 269 8.1.5 A Model for Variance Partitioning .......................... 269 ...
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ژورنال
عنوان ژورنال: BMJ
سال: 1987
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.295.6601.769